Note: Dermajuv uses Real Matrixyl® in its formulations.

Matrixyl® - Palmitoyl Pentapeptide-3
Matrixyl is the trademark name for palmitoyl pentapeptide-3, one of the powerful peptide molecules found in the latest generation of high-end anti wrinkle skin care products. This breakthrough ingredient stimulates collagen production in the skin and can even give BOTOX® injections a run for their money in the anti wrinkle department. Matryxil becomes even more effective when combined with other peptides.

Matrixyl works at the DNA Level to stimulate the very factors in the skin which we lose as we grow old... Collagen and Fibronectin. The loss of collagen is what leads to thinning skin and the wrinkling that we associate with aging skin.

Matrixyl helps to counteract this natural part of the aging process, and immediately initiate the REVERSAL of the signs of aging.

Scientifically Speaking...
Matrixyl was discovered through two branches of dermatological research with lead to wrinkle reduction and prevention. These two branches were:
1. What Causes Wrinkles
2. What Can Accelerate the healing of wounds.

You see, a wrinkle is really nothing more than a wound on the skin. Much like a wound caused by a cut or accident, a wrinkle is damage on the skin from outside forces or from the skin's inability to defend itself.

THESE TWO BRANCHES ARE EXACTLY WHAT MATRIXYL FOCUSES ON. By stimulating the DNA in the lower layers of the skin, your body's natural production of Collagen and Fibroplasts are stimulated intensely to actually trick the body into thinking it is young again. When this happens, the skin will prevent new wrinkles, and powerfully accelerate the healing of the wounds which already exist (your wrinkles).

Over six months, a clinical trial revealed that Matrixyl® temporarily produced “a highly significant reduction in the deep and moderate wrinkles,”. In fact, researchers documented changes as high as 68% (Matrixyl® 1999).
The research left no doubt: Women who had used Matrixyl® throughout the study experienced dramatic results. Further, it was proven that the longer they maintained use of Matrixyl, the more dramatic their results.



Is Matrixyl (palmitoyl pentapeptide-3) an effective anti wrinkle product?
Yes. In clinical studies, Matrixyl was shown to:
increase overall collagen synthesis by up to 117%
increase collagen IV synthesis by up to 327%
increase hyaluronic acid synthesis by up to 267%
Deep wrinkles were reduced by half. Smaller wrinkles and fine lines sometimes faded completely away. And what's even better, every participant in the study showed noticeable improvement within two weeks. The result was fewer wrinkles and younger-looking skin.



The Clinical Study
Download a PDF of the study of Matrixyl's Benefits
Matrixyl® wowed dermatologists at the Paris conference with its demonstrated effects in women. The six-month, double-blind study involved 35 women ages 34 to 72, all of whom had wrinkles (skin experts call it “photodamaged skin”). The researchers set five parameters: global area of wrinkles, density of furrows, volume of wrinkles, mean depth of the main wrinkle, and roughness of skin. Using sophisticated imaging techniques, including photometry and computerized image analysis, they measured these five markers at the beginning of the study and two months, four months, and six months later.

The women were divided into two groups. The first group of 25 women put a cream containing Matrixyl® on one side of the face and a placebo cream on the other. The other 10 put Matrixyl® cream on one side and a commercial vitamin-C cream on the other. None of the women knew which cream contained what.

The researchers reported, “A highly significant reduction in the deep and moderate wrinkles was obtained on the side treated with 3% Matrixyl®. This reduction increased with time, and a difference developed from the placebo, which never produced a significant effect. The surface area occupied by deep wrinkles was reduced by a mean of 68% over six months. The surface area occupied by moderate wrinkles was reduced by a mean of 51% over six months.”

Regarding the density of furrows, the researchers reported, “This parameter takes into account the length of the deepest wrinkles; their total sum relative to the area under analysis is used to define the density per unit area. A very marked reduction in the mean density was found for Matrixyl®, whereas the placebo tended to have the opposite effect. The results produced by Matrixyl® improved with time: -28% after two months, -31% after four months, and -47% after six months.”